First human trial of Oxford COVID-19 vaccine shows promise


However, the researchers cautioned the project was still at an early stage.

“There is still much work to be done before we can confirm if our vaccine will help manage the COVID-19 pandemic,” vaccine developer Sarah Gilbert said.

“We still do not know how strong an immune response we need to provoke to effectively protect against SARS-CoV-2 infection,” she said, adding researchers needed to learn more about COVID-19 and continue late stage trials which have already commenced.

AstraZeneca shares surged 10%, but then gave up most of those gains, to trade 1.2% stronger on the day.

AstraZeneca has signed agreements with governments around the world to supply the vaccine should it prove effective and gain regulatory approval. The company has said it will not seek to profit from the vaccine during the pandemic.

READ: Full coronavirus vaccine unlikely by next year, expert warns

Adrian Hill, the director of Oxford university’s Jenner Institute, said early projections that a million doses of the vaccine could be made by September could be an under-estimate, depending on how quickly late-stage trials can be completed.

He added it remained possible that the vaccine could be in use by the end of the year.

Researchers said the vaccine caused minor side effects more frequently than a control group, but some of these could be reduced by taking paracetamol.

AZD1222 was developed by Oxford university and licensed to AstraZeneca, which has put it into large-scale, late-stage trials to test its efficacy. It has also already signed deals to produce and supply over 2 billion doses of the shot.

The new trial included 1,077 healthy adults aged 18-55 years with no history of COVID-19.



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